Changes in arterial blood pressure after single oral administration of cuttlefish (Sepia officinalis) muscle derived peptides in spontaneously hypertensive rats

In this study we evaluated the short-term oral antihypertensive effect of several peptide sequences isolated from cuttlefish (Sepia officinalis) muscle proteins hydrolysates, previously characterized as in vitro angiotensin-I-converting enzyme-inhibitors, in spontaneously hypertensive rats (SHR).Systolic blood pressure (SBP) and the diastolic blood

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Integrative multi-omics analysis depicts the methylome and hydroxymethylome in recurrent bladder cancers and identifies biomarkers for predicting PD-L1 expression

Abstract Background Urinary bladder cancer (UBC) is a common malignancy of the urinary tract; however, the mechanism underlying its high recurrence and responses to immunotherapy folk rivet sweat remains unclear, making clinical outcome predictions difficult.Epigenetic alterations, especially DNA methylation, play important roles in bladder cancer

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Effects of materials on the tribological properties and the noise of gerotor pump used in active vibration damping system

An automobile active vibration damping system is mainly consists of a pump-controlled cylinder system with highly responsive, small volume and lightweight, the performance of the friction pair of the hydraulic pump puts forward high requirements.A compact and lightweight gerotor pump was designed, and the characteristics of the friction pair and th

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A new species of Urocopitid land snail from Haiti and a discussion of the genus Autocoptis (Gastropoda: Urocoptidae)

Autocoptis paulsoni n.sp.is described from Haiti.it is characterized by its large size, its cylindricaltapered shape, its fine costate sculpture on the teleoconch, a distinct but weak circum wella color charm 050 cooling violet basal keel and its abbreviate conical juvenile shell.it is most similar to Autocoptis gruneri (Dunker 1844), which is rede

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